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Rafał Krzysztoń. I am interested in single-cell responses to internal and external signals and in emerging mechanisms governing collective cell behavior. In my endeavors, I use methods of synthetic and quantitative biology (i.e. controlled microenvironments, synthetic gene networks, microfluidics, nanomaterials and quantitative microscopy), complementing standard biological assays. Together with Prof. Dr. Balázsi, we develop gene regulation systems allowing to explore and control cancer metastasis and to counteract viral infection. By monitoring the single-cell expression of disease-related genes and correlating it with phenotype profiles (e.g. cell motility) we aim to gain quantitative insights into emergence and dynamics of those complex pathologies. |
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Sridip Parui. The broad area of my research is the prediction of structures of biomolecules and the underlying pathways such as protein folding and conformational transitions. Knowing the three-dimensional structure and the related pathways is important for understanding biomolecular function. I believe MELD, which efficiently integrates external information with physics-based modeling, can serve these purposes. |
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Rostam Razban applies tools from statistical mechanics to elucidate underlying forces in biological phenomena, such as “Why do proteins evolve differently?”, “What causes cells to age?” and “How do brain networks transition?” Emphasis is placed on developing biophysical models for which mathematical equations with experimentally measured parameters can be derived. |
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Lakshmanji Verma |
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Ying-Jen Yang |
